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DNA Repair in Human Pluripotent Stem Cells Is Distinct from That in Non-Pluripotent Human Cells

The potential for human disease treatment using human pluripotent stem cells, including embryonic stem cells and induced pluripotent stem cells (iPSCs), also carries the risk of added genomic instability. Genomic instability is most often linked to DNA repair deficiencies, which indicates that scree...

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Detalles Bibliográficos
Autores principales: Luo, Li Z., Gopalakrishna-Pillai, Sailesh, Nay, Stephanie L., Park, Sang-Won, Bates, Steven E., Zeng, Xianmin, Iverson, Linda E., O'Connor, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295811/
https://www.ncbi.nlm.nih.gov/pubmed/22412831
http://dx.doi.org/10.1371/journal.pone.0030541