USF Binding Sequences from the HS4 Insulator Element Impose Early Replication Timing on a Vertebrate Replicator

The nuclear genomes of vertebrates show a highly organized program of DNA replication where GC-rich isochores are replicated early in S-phase, while AT-rich isochores are late replicating. GC-rich regions are gene dense and are enriched for active transcription, suggesting a connection between gene...

Descripción completa

Detalles Bibliográficos
Autores principales: Hassan-Zadeh, Vahideh, Chilaka, Sabarinadh, Cadoret, Jean-Charles, Ma, Meiji Kit-Wan, Boggetto, Nicole, West, Adam G., Prioleau, Marie-Noëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295818/
https://www.ncbi.nlm.nih.gov/pubmed/22412349
http://dx.doi.org/10.1371/journal.pbio.1001277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295818/
https://www.ncbi.nlm.nih.gov/pubmed/22412349
http://dx.doi.org/10.1371/journal.pbio.1001277

Ejemplares similares