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Novel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling
AIMS/HYPOTHESIS: Knowledge of number, size and content of insulin secretory granules is pivotal for understanding the physiology of pancreatic beta cells. Here we re-evaluated key structural features of rat beta cells, including insulin granule size, number and distribution as well as cell size. MET...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296007/ https://www.ncbi.nlm.nih.gov/pubmed/22252472 http://dx.doi.org/10.1007/s00125-011-2438-4 |