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The cytochrome c gene proximal enhancer drives activity-dependent reporter gene expression in hippocampal neurons

The proximal enhancer of the cytochrome c gene (Cycs) contains binding sites for both cAMP response element binding proteins (CREB) and Nuclear Respiratory Factor 1 (NRF1). To investigate how neuronal activity regulates this enhancer region, a lentivirus was constructed in which a short-lived green...

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Detalles Bibliográficos
Autores principales: Delgado, Jary Y., Owens, Geoffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296065/
https://www.ncbi.nlm.nih.gov/pubmed/22408605
http://dx.doi.org/10.3389/fnmol.2012.00031