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The Use of Mouse Models for Understanding the Biology of Down Syndrome and Aging

Down syndrome is a complex condition caused by trisomy of human chromosome 21. The biology of aging may be different in individuals with Down syndrome; this is not well understood in any organism. Because of its complexity, many aspects of Down syndrome must be studied either in humans or in animal...

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Detalles Bibliográficos
Autores principales: Vacano, Guido N., Duval, Nathan, Patterson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296169/
https://www.ncbi.nlm.nih.gov/pubmed/22461792
http://dx.doi.org/10.1155/2012/717315