Cargando…

A Unifying Hypothesis for Familial and Sporadic Alzheimer's Disease

Alzheimer's disease (AD) is characterised by the aggregation of two quite different proteins, namely, amyloid-beta (Aβ), which forms extracellular plaques, and tau, the main component of cytoplasmic neurofibrillary tangles. The amyloid hypothesis proposes that Aβ plaques precede tangle formatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Proctor, Carole J., Gray, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296276/
https://www.ncbi.nlm.nih.gov/pubmed/22482080
http://dx.doi.org/10.1155/2012/978742