Competing pathways control host resistance to virus via tRNA modification and programmed ribosomal frameshifting

Viral infection depends on a complex interplay between host and viral factors. Here, we link host susceptibility to viral infection to a network encompassing sulfur metabolism, tRNA modification, competitive binding, and programmed ribosomal frameshifting (PRF). We first demonstrate that the iron-su...

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Detalles Bibliográficos
Autores principales: Maynard, Nathaniel D, Macklin, Derek N, Kirkegaard, Karla, Covert, Markus W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296357/
https://www.ncbi.nlm.nih.gov/pubmed/22294093
http://dx.doi.org/10.1038/msb.2011.101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296357/
https://www.ncbi.nlm.nih.gov/pubmed/22294093
http://dx.doi.org/10.1038/msb.2011.101

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