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Weighted selective collapsing strategy for detecting rare and common variants in genetic association study
BACKGROUND: Genome-wide association studies (GWAS) have been used successfully in detecting associations between common genetic variants and complex diseases. However, common SNPs detected by current GWAS only explain a small proportion of heritable variability. With the development of next-generati...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296579/ https://www.ncbi.nlm.nih.gov/pubmed/22309429 http://dx.doi.org/10.1186/1471-2156-13-7 |