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Weighted selective collapsing strategy for detecting rare and common variants in genetic association study

BACKGROUND: Genome-wide association studies (GWAS) have been used successfully in detecting associations between common genetic variants and complex diseases. However, common SNPs detected by current GWAS only explain a small proportion of heritable variability. With the development of next-generati...

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Detalles Bibliográficos
Autores principales: Dai, Yilin, Jiang, Renfang, Dong, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296579/
https://www.ncbi.nlm.nih.gov/pubmed/22309429
http://dx.doi.org/10.1186/1471-2156-13-7