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Enhanced effects of cigarette smoke extract on inflammatory cytokine expression in IL-1β-activated human mast cells were inhibited by Baicalein via regulation of the NF-κB pathway

BACKGROUND: Human mast cells are capable of a wide variety of inflammatory responses and play a vital role in the pathogenesis of inflammatory diseases such as allergy, asthma, and atherosclerosis. We have reported that cigarette smoke extract (CSE) significantly increased IL-6 and IL-8 production i...

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Detalles Bibliográficos
Autores principales: Chi, David S, Lin, Ta-Chang, Hall, Kenton, Ha, Tuanzhu, Li, Chuanfu, Wu, Zong Doa, Soike, Thomas, Krishnaswamy, Guha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296587/
https://www.ncbi.nlm.nih.gov/pubmed/22309647
http://dx.doi.org/10.1186/1476-7961-10-3