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The impact of IL28B genotype on the gene expression profile of patients with chronic hepatitis C treated with pegylated interferon alpha and ribavirin

BACKGROUND: Recent studies of CH-C patients have demonstrated a strong association between IL28B CC genotype and sustained virologic response (SVR) after PEG-IFN/RBV treatment. We aimed to assess whether IL28B alleles rs12979860 genotype influences gene expression in response to PEG-IFN/RBV in CH-C...

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Detalles Bibliográficos
Autores principales: Younossi, Zobair M, Birerdinc, Aybike, Estep, Mike, Stepanova, Maria, Afendy, Arian, Baranova, Ancha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296607/
https://www.ncbi.nlm.nih.gov/pubmed/22313623
http://dx.doi.org/10.1186/1479-5876-10-25