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PinX1 regulation of telomerase activity and apoptosis in nasopharyngeal carcinoma cells

BACKGROUND: Human interacting protein X1 (PinX1) has been identified as a critical telomerase inhibitor and proposed to be a putative tumor suppressor gene. Loss of PinX1 has been found in a large variety of malignancies, however, its function in inhibiting telomerase activity of tumor cells is not...

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Detalles Bibliográficos
Autores principales: Lai, Xiao-Fen, Shen, Cong-Xiang, Wen, Zhong, Qian, Yu-Hong, Yu, Chao-Sheng, Wang, Jun-Qi, Zhong, Ping-Neng, Wang, Hai-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296635/
https://www.ncbi.nlm.nih.gov/pubmed/22316341
http://dx.doi.org/10.1186/1756-9966-31-12