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Gentamicin supplemented polyvinylidenfluoride mesh materials enhance tissue integration due to a transcriptionally reduced MMP-2 protein expression

BACKGROUND: A beneficial effect of gentamicin supplemented mesh material on tissue integration is known. To further elucidate the interaction of collagen and MMP-2 in chronic foreign body reaction and to determine the significance of the MMP-2-specific regulatory element (RE-1) that is known to medi...

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Detalles Bibliográficos
Autores principales: Binnebösel, Marcel, von Trotha, Klaus T, Ricken, Christina, Klink, Christian D, Junge, Karsten, Conze, Joachim, Jansen, Marc, Neumann, Ulf P, Lynen Jansen, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296653/
https://www.ncbi.nlm.nih.gov/pubmed/22244356
http://dx.doi.org/10.1186/1471-2482-12-1