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Inhibition of allergic airway responses by heparin derived oligosaccharides: identification of a tetrasaccharide sequence

BACKGROUND: Previous studies showed that heparin's anti-allergic activity is molecular weight dependent and resides in oligosaccharide fractions of <2500 daltons. OBJECTIVE: To investigate the structural sequence of heparin's anti-allergic domain, we used nitrous acid depolymerization o...

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Detalles Bibliográficos
Autores principales: Ahmed, Tahir, Smith, Gregory, Vlahov, Iontcho, Abraham, William M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296655/
https://www.ncbi.nlm.nih.gov/pubmed/22269021
http://dx.doi.org/10.1186/1465-9921-13-6