Methylation of the KEAP1 gene promoter region in human colorectal cancer

BACKGROUND: The Keap1-Nrf2 pathway has been reported to be impaired in several cancers. However, the status of Keap1-Nrf2 system in human colorectal cancer (CRC) has not been elucidated. METHODS: We used colorectal cancer (CRC) cell lines and surgical specimens to investigate the methylation status...

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Detalles Bibliográficos
Autores principales: Hanada, Naoyuki, Takahata, Takenori, Zhou, Qiliang, Ye, Xulu, Sun, Ruowen, Itoh, Jugoh, Ishiguro, Atsushi, Kijima, Hiroshi, Mimura, Junsei, Itoh, Ken, Fukuda, Shinsaku, Saijo, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296656/
https://www.ncbi.nlm.nih.gov/pubmed/22325485
http://dx.doi.org/10.1186/1471-2407-12-66

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296656/
https://www.ncbi.nlm.nih.gov/pubmed/22325485
http://dx.doi.org/10.1186/1471-2407-12-66

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