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Methylation of the KEAP1 gene promoter region in human colorectal cancer

BACKGROUND: The Keap1-Nrf2 pathway has been reported to be impaired in several cancers. However, the status of Keap1-Nrf2 system in human colorectal cancer (CRC) has not been elucidated. METHODS: We used colorectal cancer (CRC) cell lines and surgical specimens to investigate the methylation status...

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Detalles Bibliográficos
Autores principales:	Hanada, Naoyuki, Takahata, Takenori, Zhou, Qiliang, Ye, Xulu, Sun, Ruowen, Itoh, Jugoh, Ishiguro, Atsushi, Kijima, Hiroshi, Mimura, Junsei, Itoh, Ken, Fukuda, Shinsaku, Saijo, Yasuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296656/ https://www.ncbi.nlm.nih.gov/pubmed/22325485 http://dx.doi.org/10.1186/1471-2407-12-66

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