Cargando…

Skeletal Adaptation to Intramedullary Pressure-Induced Interstitial Fluid Flow Is Enhanced in Mice Subjected to Targeted Osteocyte Ablation

Interstitial fluid flow (IFF) is a potent regulatory signal in bone. During mechanical loading, IFF is generated through two distinct mechanisms that result in spatially distinct flow profiles: poroelastic interactions within the lacunar-canalicular system, and intramedullary pressurization. While t...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwon, Ronald Y., Meays, Diana R., Meilan, Alexander S., Jones, Jeremiah, Miramontes, Rosa, Kardos, Natalie, Yeh, Jiunn-Chern, Frangos, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296683/
https://www.ncbi.nlm.nih.gov/pubmed/22413015
http://dx.doi.org/10.1371/journal.pone.0033336