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Meta-Profiles of Gene Expression during Aging: Limited Similarities between Mouse and Human and an Unexpectedly Decreased Inflammatory Signature

BACKGROUND: Skin aging is associated with intrinsic processes that compromise the structure of the extracellular matrix while promoting loss of functional and regenerative capacity. These processes are accompanied by a large-scale shift in gene expression, but underlying mechanisms are not understoo...

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Detalles Bibliográficos
Autores principales: Swindell, William R., Johnston, Andrew, Sun, Liou, Xing, Xianying, Fisher, Gary J., Bulyk, Martha L., Elder, James T., Gudjonsson, Johann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296693/
https://www.ncbi.nlm.nih.gov/pubmed/22413003
http://dx.doi.org/10.1371/journal.pone.0033204