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Meta-Profiles of Gene Expression during Aging: Limited Similarities between Mouse and Human and an Unexpectedly Decreased Inflammatory Signature
BACKGROUND: Skin aging is associated with intrinsic processes that compromise the structure of the extracellular matrix while promoting loss of functional and regenerative capacity. These processes are accompanied by a large-scale shift in gene expression, but underlying mechanisms are not understoo...
Autores principales: | Swindell, William R., Johnston, Andrew, Sun, Liou, Xing, Xianying, Fisher, Gary J., Bulyk, Martha L., Elder, James T., Gudjonsson, Johann E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296693/ https://www.ncbi.nlm.nih.gov/pubmed/22413003 http://dx.doi.org/10.1371/journal.pone.0033204 |
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