MeCP2 Mutation Results in Compartment-Specific Reductions in Dendritic Branching and Spine Density in Layer 5 Motor Cortical Neurons of YFP-H Mice

Rett Syndrome (RTT) is a neurodevelopmental disorder predominantly caused by mutations in the X-linked gene MECP2. A primary feature of the syndrome is the impaired maturation and maintenance of excitatory synapses in the central nervous system (CNS). Different RTT mouse models have shown that parti...

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Detalles Bibliográficos
Autores principales: Stuss, David P., Boyd, Jamie D., Levin, David B., Delaney, Kerry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296699/
https://www.ncbi.nlm.nih.gov/pubmed/22412847
http://dx.doi.org/10.1371/journal.pone.0031896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296699/
https://www.ncbi.nlm.nih.gov/pubmed/22412847
http://dx.doi.org/10.1371/journal.pone.0031896

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