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Modeling Inhomogeneous DNA Replication Kinetics

In eukaryotic organisms, DNA replication is initiated at a series of chromosomal locations called origins, where replication forks are assembled proceeding bidirectionally to replicate the genome. The distribution and firing rate of these origins, in conjunction with the velocity at which forks prog...

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Detalles Bibliográficos
Autores principales: Gauthier, Michel G., Norio, Paolo, Bechhoefer, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296702/
https://www.ncbi.nlm.nih.gov/pubmed/22412853
http://dx.doi.org/10.1371/journal.pone.0032053