Embryonic Stem Cell-Derived Factors Inhibit T Effector Activation and Induce T Regulatory Cells by Suppressing PKC-θ Activation

Embryonic stem cells (ESCs) possess immune privileged properties and have the capacity to modulate immune activation. However, the mechanisms by which ESCs inhibit immune activation remain mostly unknown. We have previously shown that ESC-derived factors block dendritic cell maturation, thereby indi...

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Detalles Bibliográficos
Autores principales: Mohib, Kanishka, AlKhamees, Bodour, Zein, Haggag S., Allan, David, Wang, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296708/
https://www.ncbi.nlm.nih.gov/pubmed/22412871
http://dx.doi.org/10.1371/journal.pone.0032420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296708/
https://www.ncbi.nlm.nih.gov/pubmed/22412871
http://dx.doi.org/10.1371/journal.pone.0032420

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