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Evaluation of Cervical Mucosa in Transmission Bottleneck during Acute HIV-1 Infection Using a Cervical Tissue-Based Organ Culture

BACKGROUND: Although there are different strains of HIV-1 in a chronically infected individual, only one or limited virus strains are successfully transmitted to a new individual. The reason for this “transmission bottleneck” is as yet unknown. METHODOLOGY/PRINCIPAL FINDINGS: A human cervical explan...

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Detalles Bibliográficos
Autores principales: Shen, Chengli, Ding, Ming, Ratner, Deena, Montelaro, Ronald C., Chen, Yue, Gupta, Phalguni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296723/
https://www.ncbi.nlm.nih.gov/pubmed/22412886
http://dx.doi.org/10.1371/journal.pone.0032539