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Evaluation of Cervical Mucosa in Transmission Bottleneck during Acute HIV-1 Infection Using a Cervical Tissue-Based Organ Culture
BACKGROUND: Although there are different strains of HIV-1 in a chronically infected individual, only one or limited virus strains are successfully transmitted to a new individual. The reason for this “transmission bottleneck” is as yet unknown. METHODOLOGY/PRINCIPAL FINDINGS: A human cervical explan...
Autores principales: | Shen, Chengli, Ding, Ming, Ratner, Deena, Montelaro, Ronald C., Chen, Yue, Gupta, Phalguni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296723/ https://www.ncbi.nlm.nih.gov/pubmed/22412886 http://dx.doi.org/10.1371/journal.pone.0032539 |
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