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MHO1, an Evolutionarily Conserved Gene, Is Synthetic Lethal with PLC1; Mho1p Has a Role in Invasive Growth

The novel protein Memo (Mediator of ErbB2 driven cell motility) was identified in a screen for ErbB2 interacting proteins and found to have an essential function in cell motility. Memo is evolutionarily conserved with homologs found in all branches of life; the human and yeast proteins have a simila...

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Detalles Bibliográficos
Autores principales: Schlatter, Ivan D., Meira, Maria, Ueberschlag, Vanessa, Hoepfner, Dominic, Movva, Rao, Hynes, Nancy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296727/
https://www.ncbi.nlm.nih.gov/pubmed/22412880
http://dx.doi.org/10.1371/journal.pone.0032501