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MHO1, an Evolutionarily Conserved Gene, Is Synthetic Lethal with PLC1; Mho1p Has a Role in Invasive Growth
The novel protein Memo (Mediator of ErbB2 driven cell motility) was identified in a screen for ErbB2 interacting proteins and found to have an essential function in cell motility. Memo is evolutionarily conserved with homologs found in all branches of life; the human and yeast proteins have a simila...
Autores principales: | Schlatter, Ivan D., Meira, Maria, Ueberschlag, Vanessa, Hoepfner, Dominic, Movva, Rao, Hynes, Nancy E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296727/ https://www.ncbi.nlm.nih.gov/pubmed/22412880 http://dx.doi.org/10.1371/journal.pone.0032501 |
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