Low 2-Dimensional CD4 T Cell Receptor Affinity for Myelin Sets in Motion Delayed Response Kinetics

T cells recognizing self-peptides that mediate autoimmune disease and those that are responsible for efficacious immunity against pathogens may differ in affinity for antigen due to central and peripheral tolerance mechanisms. Here we utilize prototypical self-reactive (myelin) and viral-specific (L...

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Detalles Bibliográficos
Autores principales: Rosenthal, Kristen M., Edwards, Lindsay J., Sabatino, Joseph J., Hood, Jennifer D., Wasserman, Heather A., Zhu, Cheng, Evavold, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296730/
https://www.ncbi.nlm.nih.gov/pubmed/22412888
http://dx.doi.org/10.1371/journal.pone.0032562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296730/
https://www.ncbi.nlm.nih.gov/pubmed/22412888
http://dx.doi.org/10.1371/journal.pone.0032562

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