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Non-Coding Keratin Variants Associate with Liver Fibrosis Progression in Patients with Hemochromatosis

BACKGROUND: Keratins 8 and 18 (K8/K18) are intermediate filament proteins that protect the liver from various forms of injury. Exonic K8/K18 variants associate with adverse outcome in acute liver failure and with liver fibrosis progression in patients with chronic hepatitis C infection or primary bi...

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Detalles Bibliográficos
Autores principales: Strnad, Pavel, Kucukoglu, Ozlem, Lunova, Mariia, Guldiken, Nurdan, Lienau, Tim C., Stickel, Felix, Omary, M. Bishr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296740/
https://www.ncbi.nlm.nih.gov/pubmed/22412904
http://dx.doi.org/10.1371/journal.pone.0032669