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Non-Coding Keratin Variants Associate with Liver Fibrosis Progression in Patients with Hemochromatosis
BACKGROUND: Keratins 8 and 18 (K8/K18) are intermediate filament proteins that protect the liver from various forms of injury. Exonic K8/K18 variants associate with adverse outcome in acute liver failure and with liver fibrosis progression in patients with chronic hepatitis C infection or primary bi...
Autores principales: | Strnad, Pavel, Kucukoglu, Ozlem, Lunova, Mariia, Guldiken, Nurdan, Lienau, Tim C., Stickel, Felix, Omary, M. Bishr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296740/ https://www.ncbi.nlm.nih.gov/pubmed/22412904 http://dx.doi.org/10.1371/journal.pone.0032669 |
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