Integrated Epigenome Profiling of Repressive Histone Modifications, DNA Methylation and Gene Expression in Normal and Malignant Urothelial Cells

Epigenetic regulation of gene expression is commonly altered in human cancer. We have observed alterations of DNA methylation and microRNA expression that reflect the biology of bladder cancer. This common disease arises by distinct pathways with low and high-grade differentiation. We hypothesized t...

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Detalles Bibliográficos
Autores principales: Dudziec, Ewa, Gogol-Döring, Andreas, Cookson, Victoria, Chen, Wei, Catto, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296741/
https://www.ncbi.nlm.nih.gov/pubmed/22412920
http://dx.doi.org/10.1371/journal.pone.0032750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296741/
https://www.ncbi.nlm.nih.gov/pubmed/22412920
http://dx.doi.org/10.1371/journal.pone.0032750

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