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Evolution of JAK-STAT Pathway Components: Mechanisms and Role in Immune System Development
BACKGROUND: Lying downstream of a myriad of cytokine receptors, the Janus kinase (JAK) – Signal transducer and activator of transcription (STAT) pathway is pivotal for the development and function of the immune system, with additional important roles in other biological systems. To gain further insi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296744/ https://www.ncbi.nlm.nih.gov/pubmed/22412924 http://dx.doi.org/10.1371/journal.pone.0032777 |