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Evidence That Ca(2+) within the Microdomain of the L-Type Voltage Gated Ca(2+) Channel Activates ERK in MIN6 Cells in Response to Glucagon-Like Peptide-1

Glucagon like peptide-1 (GLP-1) is released from intestinal L-cells in response to nutrient ingestion and acts upon pancreatic β-cells potentiating glucose-stimulated insulin secretion and stimulating β-cell proliferation, differentiation, survival and gene transcription. These effects are mediated...

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Detalles Bibliográficos
Autores principales: Selway, Joanne, Rigatti, Roberto, Storey, Nina, Lu, Jing, Willars, Gary B., Herbert, Terence P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296766/
https://www.ncbi.nlm.nih.gov/pubmed/22412973
http://dx.doi.org/10.1371/journal.pone.0033004