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Evidence That Ca(2+) within the Microdomain of the L-Type Voltage Gated Ca(2+) Channel Activates ERK in MIN6 Cells in Response to Glucagon-Like Peptide-1
Glucagon like peptide-1 (GLP-1) is released from intestinal L-cells in response to nutrient ingestion and acts upon pancreatic β-cells potentiating glucose-stimulated insulin secretion and stimulating β-cell proliferation, differentiation, survival and gene transcription. These effects are mediated...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296766/ https://www.ncbi.nlm.nih.gov/pubmed/22412973 http://dx.doi.org/10.1371/journal.pone.0033004 |