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Targeting Bone Remodeling by Isoflavone and 3,3′-Diindolylmethane in the Context of Prostate Cancer Bone Metastasis

Prostate cancer (PCa) bone metastases have long been believed to be osteoblastic because of bone remodeling leading to the formation of new bone. However, recent studies have shown increased osteolytic activity in the beginning stages of PCa bone metastases, suggesting that targeting both osteolytic...

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Detalles Bibliográficos
Autores principales: Li, Yiwei, Kong, Dejuan, Ahmad, Aamir, Bao, Bin, Sarkar, Fazlul H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296768/
https://www.ncbi.nlm.nih.gov/pubmed/22412975
http://dx.doi.org/10.1371/journal.pone.0033011