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Neuronal autophagy and neurodegenerative diseases

Autophagy is a dynamic cellular pathway involved in the turnover of proteins, protein complexes, and organelles through lysosomal degradation. The integrity of postmitotic neurons is heavily dependent on high basal autophagy compared to non-neuronal cells as misfolded proteins and damaged organelles...

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Detalles Bibliográficos
Autores principales: Son, Jin H., Shim, Jung Hee, Kim, Kyung-Hee, Ha, Ji-Young, Han, Ji Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296817/
https://www.ncbi.nlm.nih.gov/pubmed/22257884
http://dx.doi.org/10.3858/emm.2012.44.2.031