Hydrodynamic delivery of plasmid DNA encoding human FcγR-Ig dimers blocks immune-complex mediated inflammation in mice

Therapeutic use and function of recombinant molecules can be studied by the expression of foreign genes in mice. In this study, we have expressed human Fcgamma receptor –Ig fusion molecules (FcγR-Igs) in mice by administering FcγR-Ig plasmid DNAs hydrodynamically and compared their effectiveness to...

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Detalles Bibliográficos
Autores principales: Shashidharamurthy, Rangaiah, Machiah, Deepa, Bozeman, Erica N., Srivatsan, Sanjay, Patel, Jaina, Cho, Alice, Jacob, Joshy, Selvaraj, Periasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296821/
https://www.ncbi.nlm.nih.gov/pubmed/22113315
http://dx.doi.org/10.1038/gt.2011.175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296821/
https://www.ncbi.nlm.nih.gov/pubmed/22113315
http://dx.doi.org/10.1038/gt.2011.175

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