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A Quantitative Basis for Antiretroviral Therapy for HIV-1 Infection

Highly active antiretroviral therapy (HAART)(1–3) has dramatically decreased mortality from HIV-1 infection(4) and is a major achievement of modern medicine. However, there is no fundamental theory of HAART. Elegant models describe the dynamics of viral replication(3,5–9), but a metric for the antiv...

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Detalles Bibliográficos
Autores principales: Jilek, Benjamin L., Zarr, Melissa, Sampah, Maame E., Rabi, S. Alireza, Bullen, Cynthia K., Lai, Jun, Shen, Lin, Siliciano, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296892/
https://www.ncbi.nlm.nih.gov/pubmed/22344296
http://dx.doi.org/10.1038/nm.2649