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Selective mGluR1 Antagonist EMQMCM Inhibits the Kainate-Induced Excitotoxicity in Primary Neuronal Cultures and in the Rat Hippocampus

Abundant evidence suggests that indirect inhibitory modulation of glutamatergic transmission, via metabotropic glutamatergic receptors (mGluR), may induce neuroprotection. The present study was designed to determine whether the selective antagonist of mGluR1 (3-ethyl-2-methyl-quinolin-6-yl)-(4-metho...

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Detalles Bibliográficos
Autores principales: Śmiałowska, Maria, Gołembiowska, Krystyna, Kajta, Małgorzata, Zięba, Barbara, Dziubina, Anna, Domin, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296950/
https://www.ncbi.nlm.nih.gov/pubmed/22144346
http://dx.doi.org/10.1007/s12640-011-9293-4