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Disruption of CTCF at the miR-125b1 locus in gynecological cancers

BACKGROUND: In cancer cells, transcriptional gene silencing has been associated with genetic and epigenetic defects. The disruption of DNA methylation patterns and covalent histone marks has been associated with cancer development. Until recently, microRNA (miRNA) gene silencing was not well underst...

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Detalles Bibliográficos
Autores principales: Soto-Reyes, Ernesto, González-Barrios, Rodrigo, Cisneros-Soberanis, Fernanda, Herrera-Goepfert, Roberto, Pérez, Víctor, Cantú, David, Prada, Diddier, Castro, Clementina, Recillas-Targa, Félix, Herrera, Luis A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297514/
https://www.ncbi.nlm.nih.gov/pubmed/22277129
http://dx.doi.org/10.1186/1471-2407-12-40