Cargando…
Disruption of CTCF at the miR-125b1 locus in gynecological cancers
BACKGROUND: In cancer cells, transcriptional gene silencing has been associated with genetic and epigenetic defects. The disruption of DNA methylation patterns and covalent histone marks has been associated with cancer development. Until recently, microRNA (miRNA) gene silencing was not well underst...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297514/ https://www.ncbi.nlm.nih.gov/pubmed/22277129 http://dx.doi.org/10.1186/1471-2407-12-40 |