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DNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4)

BACKGROUND: Vascular Endothelial Growth Factors (VEGFs) and their receptors (VEGF-Rs) are important regulators for angiogenesis and lymphangiogenesis. VEGFs and VEGF-Rs are not only expressed on endothelial cells but also on various subtypes of solid tumors and leukemias contributing to the growth o...

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Detalles Bibliográficos
Autores principales: Quentmeier, Hilmar, Eberth, Sonja, Romani, Julia, Weich, Herbert A, Zaborski, Margarete, Drexler, Hans G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297533/
https://www.ncbi.nlm.nih.gov/pubmed/22251800
http://dx.doi.org/10.1186/1471-2407-12-19