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Beyond the Binding Site: The Role of the β2 – β3 Loop and Extra-Domain Structures in PDZ Domains

A general paradigm to understand protein function is to look at properties of isolated well conserved domains, such as SH3 or PDZ domains. While common features of domain families are well understood, the role of subtle differences among members of these families is less clear. Here, molecular dynam...

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Detalles Bibliográficos
Autores principales: Mostarda, Stefano, Gfeller, David, Rao, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297566/
https://www.ncbi.nlm.nih.gov/pubmed/22412368
http://dx.doi.org/10.1371/journal.pcbi.1002429