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Exploring the Complexity of the HIV-1 Fitness Landscape
Although fitness landscapes are central to evolutionary theory, so far no biologically realistic examples for large-scale fitness landscapes have been described. Most currently available biological examples are restricted to very few loci or alleles and therefore do not capture the high dimensionali...
Autores principales: | Kouyos, Roger D., Leventhal, Gabriel E., Hinkley, Trevor, Haddad, Mojgan, Whitcomb, Jeannette M., Petropoulos, Christos J., Bonhoeffer, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297571/ https://www.ncbi.nlm.nih.gov/pubmed/22412384 http://dx.doi.org/10.1371/journal.pgen.1002551 |
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