The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines

Type 1 diabetes (T1D) is an autoimmune disease in which pancreatic beta cells are killed by infiltrating immune cells and by cytokines released by these cells. Signaling events occurring in the pancreatic beta cells are decisive for their survival or death in diabetes. We have used RNA sequencing (R...

Descripción completa

Detalles Bibliográficos
Autores principales: Eizirik, Décio L., Sammeth, Michael, Bouckenooghe, Thomas, Bottu, Guy, Sisino, Giorgia, Igoillo-Esteve, Mariana, Ortis, Fernanda, Santin, Izortze, Colli, Maikel L., Barthson, Jenny, Bouwens, Luc, Hughes, Linda, Gregory, Lorna, Lunter, Gerton, Marselli, Lorella, Marchetti, Piero, McCarthy, Mark I., Cnop, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297576/
https://www.ncbi.nlm.nih.gov/pubmed/22412385
http://dx.doi.org/10.1371/journal.pgen.1002552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297576/
https://www.ncbi.nlm.nih.gov/pubmed/22412385
http://dx.doi.org/10.1371/journal.pgen.1002552

Ejemplares similares