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Repression of Germline RNAi Pathways in Somatic Cells by Retinoblastoma Pathway Chromatin Complexes

The retinoblastoma (Rb) tumor suppressor acts with a number of chromatin cofactors in a wide range of species to suppress cell proliferation. The Caenorhabditis elegans retinoblastoma gene and many of these cofactors, called synMuv B genes, were identified in genetic screens for cell lineage defects...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoyun, Shi, Zhen, Cui, Mingxue, Han, Min, Ruvkun, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297578/
https://www.ncbi.nlm.nih.gov/pubmed/22412383
http://dx.doi.org/10.1371/journal.pgen.1002542