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Repression of Germline RNAi Pathways in Somatic Cells by Retinoblastoma Pathway Chromatin Complexes
The retinoblastoma (Rb) tumor suppressor acts with a number of chromatin cofactors in a wide range of species to suppress cell proliferation. The Caenorhabditis elegans retinoblastoma gene and many of these cofactors, called synMuv B genes, were identified in genetic screens for cell lineage defects...
Autores principales: | Wu, Xiaoyun, Shi, Zhen, Cui, Mingxue, Han, Min, Ruvkun, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297578/ https://www.ncbi.nlm.nih.gov/pubmed/22412383 http://dx.doi.org/10.1371/journal.pgen.1002542 |
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