Whole Genome Deep Sequencing of HIV-1 Reveals the Impact of Early Minor Variants Upon Immune Recognition During Acute Infection

Deep sequencing technologies have the potential to transform the study of highly variable viral pathogens by providing a rapid and cost-effective approach to sensitively characterize rapidly evolving viral quasispecies. Here, we report on a high-throughput whole HIV-1 genome deep sequencing platform...

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Detalles Bibliográficos
Autores principales: Henn, Matthew R., Boutwell, Christian L., Charlebois, Patrick, Lennon, Niall J., Power, Karen A., Macalalad, Alexander R., Berlin, Aaron M., Malboeuf, Christine M., Ryan, Elizabeth M., Gnerre, Sante, Zody, Michael C., Erlich, Rachel L., Green, Lisa M., Berical, Andrew, Wang, Yaoyu, Casali, Monica, Streeck, Hendrik, Bloom, Allyson K., Dudek, Tim, Tully, Damien, Newman, Ruchi, Axten, Karen L., Gladden, Adrianne D., Battis, Laura, Kemper, Michael, Zeng, Qiandong, Shea, Terrance P., Gujja, Sharvari, Zedlack, Carmen, Gasser, Olivier, Brander, Christian, Hess, Christoph, Günthard, Huldrych F., Brumme, Zabrina L., Brumme, Chanson J., Bazner, Suzane, Rychert, Jenna, Tinsley, Jake P., Mayer, Ken H., Rosenberg, Eric, Pereyra, Florencia, Levin, Joshua Z., Young, Sarah K., Jessen, Heiko, Altfeld, Marcus, Birren, Bruce W., Walker, Bruce D., Allen, Todd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297584/
https://www.ncbi.nlm.nih.gov/pubmed/22412369
http://dx.doi.org/10.1371/journal.ppat.1002529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297584/
https://www.ncbi.nlm.nih.gov/pubmed/22412369
http://dx.doi.org/10.1371/journal.ppat.1002529

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