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Influenza A Virus Infection of Human Primary Dendritic Cells Impairs Their Ability to Cross-Present Antigen to CD8 T Cells

Influenza A virus (IAV) infection is normally controlled by adaptive immune responses initiated by dendritic cells (DCs). We investigated the consequences of IAV infection of human primary DCs on their ability to function as antigen-presenting cells. IAV was internalized by both myeloid DCs (mDCs) a...

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Detalles Bibliográficos
Autores principales: Smed-Sörensen, Anna, Chalouni, Cécile, Chatterjee, Bithi, Cohn, Lillian, Blattmann, Peter, Nakamura, Norihiro, Delamarre, Lélia, Mellman, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297599/
https://www.ncbi.nlm.nih.gov/pubmed/22412374
http://dx.doi.org/10.1371/journal.ppat.1002572