CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and Production of Pathogenic IgG-Antibodies

BACKGROUND: Adipose tissue inflammation fuels the metabolic syndrome. We recently reported that CD40L – an established marker and mediator of cardiovascular disease – induces inflammatory cytokine production in adipose cells in vitro. Here, we tested the hypothesis that CD40L deficiency modulates ad...

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Detalles Bibliográficos
Autores principales: Wolf, Dennis, Jehle, Felix, Ortiz Rodriguez, Alexandra, Dufner, Bianca, Hoppe, Natalie, Colberg, Christian, Lozhkin, Andrey, Bassler, Nicole, Rupprecht, Benjamin, Wiedemann, Ansgar, Hilgendorf, Ingo, Stachon, Peter, Willecke, Florian, Febbraio, Mark, Binder, Christoph J., Bode, Christoph, Zirlik, Andreas, Peter, Karlheinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297623/
https://www.ncbi.nlm.nih.gov/pubmed/22412980
http://dx.doi.org/10.1371/journal.pone.0033026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297623/
https://www.ncbi.nlm.nih.gov/pubmed/22412980
http://dx.doi.org/10.1371/journal.pone.0033026

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