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Activation of Interferon Regulatory Factor 5 by Site Specific Phosphorylation
The cellular defense to infection depends on accurate activation of transcription factors and expression of select innate immunity genes. Interferon regulatory factor 5 (IRF5), a risk factor for systemic lupus erythematosus, is activated in response to pathogen recognition receptor engagement and do...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297630/ https://www.ncbi.nlm.nih.gov/pubmed/22412986 http://dx.doi.org/10.1371/journal.pone.0033098 |