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Cellular Immunity Confers Transient Protection in Experimental Buruli Ulcer following BCG or Mycolactone-Negative Mycobacterium ulcerans Vaccination

BACKGROUND: Buruli ulcer (BU) is an emerging infectious disease caused by Mycobacterium ulcerans that can result in extensive necrotizing cutaneous lesions due to the cytotoxic exotoxin mycolactone. There is no specific vaccine against BU but reports show some degree of cross-reactive protection con...

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Detalles Bibliográficos
Autores principales: Fraga, Alexandra G., Martins, Teresa G., Torrado, Egídio, Huygen, Kris, Portaels, Françoise, Silva, Manuel T., Castro, António G., Pedrosa, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297633/
https://www.ncbi.nlm.nih.gov/pubmed/22413022
http://dx.doi.org/10.1371/journal.pone.0033406