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Removing technical variability in RNA-seq data using conditional quantile normalization

The ability to measure gene expression on a genome-wide scale is one of the most promising accomplishments in molecular biology. Microarrays, the technology that first permitted this, were riddled with problems due to unwanted sources of variability. Many of these problems are now mitigated, after a...

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Detalles Bibliográficos
Autores principales: Hansen, Kasper D., Irizarry, Rafael A., WU, Zhijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297825/
https://www.ncbi.nlm.nih.gov/pubmed/22285995
http://dx.doi.org/10.1093/biostatistics/kxr054