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Outgrowth of Single Oncogene-expressing Cells from Suppressive Epithelial Environments
Tumorigenesis is a clonal evolution process initiated from single cells within otherwise histologically normal tissue(1). How single, sporadic mutant cells that have sustained oncogenic alterations evolve within tightly regulated tissue environment remains elusive. Here, we investigated the effects...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297969/ https://www.ncbi.nlm.nih.gov/pubmed/22318515 http://dx.doi.org/10.1038/nature10826 |